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1/30/2012
Cancer drugs affect mouse genomes for generations: DNA mutations continue to accumulate in offspring of treated mice. Three common chemotherapy drugs cause DNA mutations not only in mice that receive treatment, but also in their offspring, according to a study published today in the Proceedings of the National Academy of Sciences USA1.
The results suggest that the genome in treated mice became destabilized yielding new mutations long after exposure to the drugs has ceased. A similar phenomenon has been observed in mice exposed to radiation.
Genomic damage can be seen in the offspring of mice who have received chemotherapy drugs. (Nature)
Transgenic DNA introgressed into traditional maize landraces in Oaxaca, Mexico Concerns have been raised about the potential effects of transgenic introductions on the genetic diversity of crop landraces and wild relatives in areas of crop origin and diversification, as this diversity is considered essential for global food security (Nature)
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